The Challenge: Inefficient Audience Targeting

Most marketing teams know they are wasting ad spend, but not exactly where. Campaigns run on coarse demographic segments, lookalikes, and broad interests, hoping the algorithm finds the right people. Without the time or tooling to continuously refine segments, marketers end up paying for impressions and clicks from audiences that were never likely to convert in the first place.

Traditional approaches to audience targeting were built for a simpler environment: a few main channels, slower feedback loops, and limited data. Excel-based persona workshops, manual lookalike setups, and gut-feel targeting criteria cannot keep pace with today’s fragmented customer journeys and fast-moving auctions. As platforms automate more mechanics, the real advantage lies in who you target and how you structure tests — an area where manual processes are simply too slow and inconsistent.

The business impact is clear: higher customer acquisition costs, underperforming campaigns that are hard to debug, and a growing gap to competitors who are more data-driven. Budget gets locked into mediocre segments, leaving little room to explore new audiences or creative angles. Over time, this doesn’t just hurt ROAS — it weakens your understanding of your market, your ability to personalize, and your confidence in scaling campaigns.

The good news: this problem is solvable. With the right use of AI in marketing, especially tools like ChatGPT, you can turn scattered research, CRM exports, and campaign performance data into sharper personas, concrete segment hypotheses, and structured audience experiments. At Reruption, we’ve helped companies build AI-powered decision tools and workflows that replace manual guesswork with repeatable, testable targeting strategies. The sections below walk through how you can apply similar thinking to your own ad accounts.

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Our Assessment

A strategic assessment of the challenge and high-level tips how to tackle it.

From Reruption's work embedding AI inside organisations, we see a clear pattern: companies that win in paid media treat audience targeting as a continuous learning system, not a one-off exercise. Used correctly, ChatGPT for marketing becomes a thinking partner that translates qualitative research, CRM data, and campaign results into sharper segments and test plans, instead of yet another generic copywriting tool.

Think in Hypotheses, Not Finished Personas

Most teams treat personas as static artifacts: a slide or PDF that rarely changes, even as markets evolve. To fix inefficient targeting, you need to shift towards a hypothesis-driven approach: every audience definition is a bet that can be tested and refined. ChatGPT is ideal for helping you formulate and structure these bets.

Feed ChatGPT your existing personas, qualitative research notes, and high-level campaign results, and ask it to propose specific audience hypotheses (e.g. “tool-focused DIY managers” vs. “process-focused operations leaders”). This moves your team away from vague labels and towards clear, testable audience definitions that reflect behaviour, pains, and triggers — not just age and location.

Connect Qualitative Insight with Quantitative Targeting

Marketers often have rich qualitative insights from sales calls, NPS comments, or customer interviews, but struggle to translate them into actionable ad targeting criteria. ChatGPT can act as the bridge between what customers say and how platforms allow you to target them.

Strategically, this means giving ChatGPT both your raw qualitative inputs and your channel-specific constraints (what targeting options exist in Meta, Google, LinkedIn, etc.). The goal is not for AI to pick audiences for you, but to surface structured mappings: “this pain point typically correlates with these interests, job titles, or in-market segments.” That mapping becomes a foundation for scalable, cross-channel audience strategies.

Make Audience Design a Cross-Functional Discipline

Audience quality is rarely just a marketing problem. Sales, product, and customer success all hold critical pieces of the puzzle: who closes fast, who churns early, who becomes a power user. A strategic use of ChatGPT in audience targeting is to synthesise these perspectives into shared segment definitions.

Use AI during cross-functional workshops: paste anonymised CRM exports, win/loss notes, and support tags into ChatGPT and ask it to propose segment archetypes and key discriminators. This encourages a shared language around “good customers” and ensures your media targeting aligns with revenue reality, not just channel metrics.

Guard Against Overfitting and Stereotyping

The risk with AI-assisted targeting is that the models mirror your existing biases or overfit to small data sets. Strategically, you need governance: clear rules for what ChatGPT can suggest and what still requires human judgment or experimentation before scaling budgets.

Set expectations inside your team that anything produced by ChatGPT is a starting point, not a decision. Combine its suggestions with sanity checks: is this segment large enough? Are we unintentionally excluding high-value subgroups? Are we stereotyping based on demographics instead of behaviour? Building these questions into your process keeps AI marketing helpful instead of harmful.

Design for Continuous Learning, Not One-Off Cleanup

Using ChatGPT once to clean up your audiences will give a short-term ROAS bump, but the real upside comes from embedding it into your ongoing optimisation cycle. Strategically, your goal should be a repeatable loop: data → AI-assisted insight → new tests → new data.

Set a recurring cadence (e.g. monthly or per campaign cycle) where ChatGPT reviews performance summaries and surfaces underperforming segments, new hypotheses, and ideas for refinement. Over time, this turns inefficient targeting into a continuously improving system, rather than a recurring fire drill before each big product launch or quarter-end push.

Used as a structured thinking partner, ChatGPT helps marketing teams move from vague, inefficient audiences to precise segment hypotheses, aligned with real business outcomes. Instead of guessing who to target, you systematically translate data and qualitative insight into testable definitions that improve ROAS over time. At Reruption, we specialise in turning this approach into working tools and workflows inside your organisation — from rapid PoCs to embedded AI assistants for your marketing teams. If you want to explore how this could look in your specific ad stack, we’re happy to discuss concrete options without the slides-first consulting theater.

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Real-World Case Studies

From Healthcare to News Media: Learn how companies successfully use ChatGPT.

AstraZeneca

Healthcare

In the highly regulated pharmaceutical industry, AstraZeneca faced immense pressure to accelerate drug discovery and clinical trials, which traditionally take 10-15 years and cost billions, with low success rates of under 10%. Data silos, stringent compliance requirements (e.g., FDA regulations), and manual knowledge work hindered efficiency across R&D and business units. Researchers struggled with analyzing vast datasets from 3D imaging, literature reviews, and protocol drafting, leading to delays in bringing therapies to patients. Scaling AI was complicated by data privacy concerns, integration into legacy systems, and ensuring AI outputs were reliable in a high-stakes environment. Without rapid adoption, AstraZeneca risked falling behind competitors leveraging AI for faster innovation toward 2030 ambitions of novel medicines.

Lösung

AstraZeneca launched an enterprise-wide generative AI strategy, deploying ChatGPT Enterprise customized for pharma workflows. This included AI assistants for 3D molecular imaging analysis, automated clinical trial protocol drafting, and knowledge synthesis from scientific literature. They partnered with OpenAI for secure, scalable LLMs and invested in training: ~12,000 employees across R&D and functions completed GenAI programs by mid-2025. Infrastructure upgrades, like AMD Instinct MI300X GPUs, optimized model training. Governance frameworks ensured compliance, with human-in-loop validation for critical tasks. Rollout phased from pilots in 2023-2024 to full scaling in 2025, focusing on R&D acceleration via GenAI for molecule design and real-world evidence analysis.

Ergebnisse

  • ~12,000 employees trained on generative AI by mid-2025
  • 85-93% of staff reported productivity gains
  • 80% of medical writers found AI protocol drafts useful
  • Significant reduction in life sciences model training time via MI300X GPUs
  • High AI maturity ranking per IMD Index (top global)
  • GenAI enabling faster trial design and dose selection
Read case study →

AT&T

Telecommunications

As a leading telecom operator, AT&T manages one of the world's largest and most complex networks, spanning millions of cell sites, fiber optics, and 5G infrastructure. The primary challenges included inefficient network planning and optimization, such as determining optimal cell site placement and spectrum acquisition amid exploding data demands from 5G rollout and IoT growth. Traditional methods relied on manual analysis, leading to suboptimal resource allocation and higher capital expenditures. Additionally, reactive network maintenance caused frequent outages, with anomaly detection lagging behind real-time needs. Detecting and fixing issues proactively was critical to minimize downtime, but vast data volumes from network sensors overwhelmed legacy systems. This resulted in increased operational costs, customer dissatisfaction, and delayed 5G deployment. AT&T needed scalable AI to predict failures, automate healing, and forecast demand accurately.

Lösung

AT&T integrated machine learning and predictive analytics through its AT&T Labs, developing models for network design including spectrum refarming and cell site optimization. AI algorithms analyze geospatial data, traffic patterns, and historical performance to recommend ideal tower locations, reducing build costs. For operations, anomaly detection and self-healing systems use predictive models on NFV (Network Function Virtualization) to forecast failures and automate fixes, like rerouting traffic. Causal AI extends beyond correlations for root-cause analysis in churn and network issues. Implementation involved edge-to-edge intelligence, deploying AI across 100,000+ engineers' workflows.

Ergebnisse

  • Billions of dollars saved in network optimization costs
  • 20-30% improvement in network utilization and efficiency
  • Significant reduction in truck rolls and manual interventions
  • Proactive detection of anomalies preventing major outages
  • Optimized cell site placement reducing CapEx by millions
  • Enhanced 5G forecasting accuracy by up to 40%
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Airbus

Aerospace

In aircraft design, computational fluid dynamics (CFD) simulations are essential for predicting airflow around wings, fuselages, and novel configurations critical to fuel efficiency and emissions reduction. However, traditional high-fidelity RANS solvers require hours to days per run on supercomputers, limiting engineers to just a few dozen iterations per design cycle and stifling innovation for next-gen hydrogen-powered aircraft like ZEROe. This computational bottleneck was particularly acute amid Airbus' push for decarbonized aviation by 2035, where complex geometries demand exhaustive exploration to optimize lift-drag ratios while minimizing weight. Collaborations with DLR and ONERA highlighted the need for faster tools, as manual tuning couldn't scale to test thousands of variants needed for laminar flow or blended-wing-body concepts.

Lösung

Machine learning surrogate models, including physics-informed neural networks (PINNs), were trained on vast CFD datasets to emulate full simulations in milliseconds. Airbus integrated these into a generative design pipeline, where AI predicts pressure fields, velocities, and forces, enforcing Navier-Stokes physics via hybrid loss functions for accuracy. Development involved curating millions of simulation snapshots from legacy runs, GPU-accelerated training, and iterative fine-tuning with experimental wind-tunnel data. This enabled rapid iteration: AI screens designs, high-fidelity CFD verifies top candidates, slashing overall compute by orders of magnitude while maintaining <5% error on key metrics.

Ergebnisse

  • Simulation time: 1 hour → 30 ms (120,000x speedup)
  • Design iterations: +10,000 per cycle in same timeframe
  • Prediction accuracy: 95%+ for lift/drag coefficients
  • 50% reduction in design phase timeline
  • 30-40% fewer high-fidelity CFD runs required
  • Fuel burn optimization: up to 5% improvement in predictions
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Amazon

Retail

In the vast e-commerce landscape, online shoppers face significant hurdles in product discovery and decision-making. With millions of products available, customers often struggle to find items matching their specific needs, compare options, or get quick answers to nuanced questions about features, compatibility, and usage. Traditional search bars and static listings fall short, leading to shopping cart abandonment rates as high as 70% industry-wide and prolonged decision times that frustrate users. Amazon, serving over 300 million active customers, encountered amplified challenges during peak events like Prime Day, where query volumes spiked dramatically. Shoppers demanded personalized, conversational assistance akin to in-store help, but scaling human support was impossible. Issues included handling complex, multi-turn queries, integrating real-time inventory and pricing data, and ensuring recommendations complied with safety and accuracy standards amid a $500B+ catalog.

Lösung

Amazon developed Rufus, a generative AI-powered conversational shopping assistant embedded in the Amazon Shopping app and desktop. Rufus leverages a custom-built large language model (LLM) fine-tuned on Amazon's product catalog, customer reviews, and web data, enabling natural, multi-turn conversations to answer questions, compare products, and provide tailored recommendations. Powered by Amazon Bedrock for scalability and AWS Trainium/Inferentia chips for efficient inference, Rufus scales to millions of sessions without latency issues. It incorporates agentic capabilities for tasks like cart addition, price tracking, and deal hunting, overcoming prior limitations in personalization by accessing user history and preferences securely. Implementation involved iterative testing, starting with beta in February 2024, expanding to all US users by September, and global rollouts, addressing hallucination risks through grounding techniques and human-in-loop safeguards.

Ergebnisse

  • 60% higher purchase completion rate for Rufus users
  • $10B projected additional sales from Rufus
  • 250M+ customers used Rufus in 2025
  • Monthly active users up 140% YoY
  • Interactions surged 210% YoY
  • Black Friday sales sessions +100% with Rufus
  • 149% jump in Rufus users recently
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American Eagle Outfitters

Apparel Retail

In the competitive apparel retail landscape, American Eagle Outfitters faced significant hurdles in fitting rooms, where customers crave styling advice, accurate sizing, and complementary item suggestions without waiting for overtaxed associates . Peak-hour staff shortages often resulted in frustrated shoppers abandoning carts, low try-on rates, and missed conversion opportunities, as traditional in-store experiences lagged behind personalized e-commerce . Early efforts like beacon technology in 2014 doubled fitting room entry odds but lacked depth in real-time personalization . Compounding this, data silos between online and offline hindered unified customer insights, making it tough to match items to individual style preferences, body types, or even skin tones dynamically. American Eagle needed a scalable solution to boost engagement and loyalty in flagship stores while experimenting with AI for broader impact .

Lösung

American Eagle partnered with Aila Technologies to deploy interactive fitting room kiosks powered by computer vision and machine learning, rolled out in 2019 at flagship locations in Boston, Las Vegas, and San Francisco . Customers scan garments via iOS devices, triggering CV algorithms to identify items and ML models—trained on purchase history and Google Cloud data—to suggest optimal sizes, colors, and outfit complements tailored to inferred style and preferences . Integrated with Google Cloud's ML capabilities, the system enables real-time recommendations, associate alerts for assistance, and seamless inventory checks, evolving from beacon lures to a full smart assistant . This experimental approach, championed by CMO Craig Brommers, fosters an AI culture for personalization at scale .

Ergebnisse

  • Double-digit conversion gains from AI personalization
  • 11% comparable sales growth for Aerie brand Q3 2025
  • 4% overall comparable sales increase Q3 2025
  • 29% EPS growth to $0.53 Q3 2025
  • Doubled fitting room try-on odds via early tech
  • Record Q3 revenue of $1.36B
Read case study →

Best Practices

Successful implementations follow proven patterns. Have a look at our tactical advice to get started.

Turn CRM and Analytics Data into Testable Audience Segments

Start by exporting anonymised data from your CRM and analytics tools: deals won/lost, LTV, key product usage patterns, and source campaigns. Your goal is to let ChatGPT identify patterns that define high-value vs. low-value customers and convert these into ad-ready audience definitions.

Structure your export with clear columns (industry, job title, company size, product purchased, LTV band, acquisition channel, etc.). Then use a prompt like:

Act as a marketing data strategist.
You will receive anonymised CRM data and should:
1) Identify 3-5 high-value customer archetypes based on LTV and conversion speed
2) Describe their key attributes (company profile, role, behaviours, pains)
3) Convert each archetype into ad platform targeting suggestions for:
   - Meta (interests, behaviours, lookalike seeds)
   - Google (in-market, custom segments, keywords themes)
   - LinkedIn (job titles, functions, industries, seniority)

Here is the data (CSV excerpt):
[PASTE EXPORT HERE]

This gives you concrete segment definitions and targeting handles you can map into your platforms, instead of starting from a blank screen.

Translate Qualitative Feedback into Targeting Criteria

Collect raw qualitative data: customer interviews, sales call notes, survey responses, support tickets. The aim is to capture language around use cases, motivations, objections, and triggers. Feed this into ChatGPT with a clear transformation task.

Example prompt:

You are an AI assistant helping with audience targeting.
Below are anonymised customer quotes, interview notes, and sales objections.

Task:
1) Cluster customers into 4-6 segments based on their primary job-to-be-done and pain points
2) For each segment, provide:
   - A segment name
   - Key problem statements in their own words
   - Typical decision triggers
   - Suggested targeting criteria for Meta, Google, and LinkedIn
3) Suggest 2-3 A/B test ideas per segment (e.g. angle, offer, creative focus).

Here are the notes:
[PASTE NOTES HERE]

Use the output to refine audiences and craft segment-specific campaigns, instead of reusing the same generic messaging for everyone.

Use ChatGPT to Design a Structured Audience Testing Roadmap

Many accounts have dozens of overlapping audiences and very little learning. Use ChatGPT to design a clear testing roadmap that prioritises which audiences to test, in which order, and with what success criteria.

Prepare a simple summary of your current targeting setup: audience types, approximate sizes, historic ROAS/CAC, and channel mix. Then run this prompt:

Act as a performance marketing strategist.
Here is an overview of our current audiences and performance:
[DESCRIBE AUDIENCES + METRICS]

Please:
1) Identify redundant or overlapping audiences that we should consolidate
2) Propose a 4-6 week audience testing roadmap, including:
   - Priority segments to test
   - Budget allocation guidelines
   - Primary KPIs (e.g. CAC, ROAS, lead quality proxy)
3) Define a simple test log structure I can use to track learnings.

Implement the roadmap in your ad platforms, using the test log structure to capture learnings that can be fed back into ChatGPT for further optimisation.

Create Channel-Specific Audience Briefs for Media Buyers

Even if you outsource buying to agencies or have separate channel specialists, you can keep strategic control of audience definition by giving them structured briefs created with ChatGPT. This avoids misinterpretation and ensures consistency across channels.

Once you have your key segments, ask ChatGPT to convert them into briefing templates:

You are helping me prepare channel-specific audience briefs.
Here are our 4 key audience segments:
[SHORT SEGMENT DESCRIPTIONS]

For each segment, create a brief including:
- Segment narrative (who they are, what they care about)
- Targeting recommendations for Meta, Google, and LinkedIn
- Negative audience suggestions (who to exclude)
- Key do's and don'ts for creative and messaging.

Output in a structured, copy-paste-friendly format.

Share these briefs with agencies or channel owners so that targeting choices align with your strategic segments, not with whoever set up the campaign last.

Automate Periodic Audience Reviews with ChatGPT

Build a lightweight routine where, every 2–4 weeks, you export performance data by audience and let ChatGPT surface where your targeting is inefficient. Focus on spend, conversions, ROAS, and any lead quality proxies you have (e.g. MQL/SQL rates).

Example workflow:

1) Export performance by audience/ad set from your ad platforms.
2) Clean the export: keep columns like audience name, spend, conversions, CPA, ROAS, etc.
3) Paste a summary into ChatGPT with this prompt:

"Act as a performance analyst.
Here is audience-level performance data:
[PASTE SUMMARY]

Please:
- Flag audiences that are clearly inefficient and should be paused
- Suggest which audiences deserve more budget
- Propose 3-5 new or refined audience hypotheses based on this data
- Recommend specific next steps for the next 2 weeks."

4) Implement the recommendations and track impact.

This turns audience optimisation into a recurring, semi-automated process rather than an ad-hoc clean-up when performance drops.

Use Guardrail Prompts to Keep Outputs Actionable and Compliant

To keep ChatGPT’s suggestions usable and compliant with your policies, embed guardrails directly into your prompts. Explicitly instruct it to avoid sensitive targeting categories and to respect platform rules and your internal guidelines.

For example:

You are assisting with digital advertising audience strategy.
Important rules:
- Do NOT suggest targeting based on sensitive attributes (health, religion, ethnicity, etc.)
- Follow Meta, Google, and LinkedIn ad policies at a high level
- Prioritise behavioural, contextual, and business attributes.

Task:
Using the segments below, propose compliant and scalable targeting ideas:
[PASTE SEGMENTS]

This ensures your AI-assisted audience targeting stays aligned with legal, ethical, and platform requirements.

When applied consistently, these practices typically lead to clearer segment definitions, cleaner account structures, and more focused experiments. Marketing teams we see adopt similar workflows often achieve 10–25% improvements in ROAS over several optimisation cycles, not from magic algorithms, but from systematically removing audience waste and learning faster from their data.

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Frequently Asked Questions

ChatGPT helps by turning your existing data and insights into structured, testable audience definitions. Instead of starting from generic interests or broad lookalikes, you feed ChatGPT CRM exports, campaign performance summaries, and qualitative feedback.

It then proposes refined personas, segment hypotheses, and concrete targeting criteria for platforms like Meta, Google, and LinkedIn. You still control decisions and budgets, but you move from guesswork to a systematic, AI-assisted way of designing and refining audiences.

You don’t need a data science team to start. The core requirements are:

  • Someone who understands your customers and funnel (e.g. performance marketer, growth lead)
  • Access to basic data: CRM exports, campaign reports, analytics snapshots
  • A clear process owner who can turn ChatGPT outputs into concrete changes in your ad accounts

Technical depth becomes more important when you want to automate parts of the workflow (e.g. scheduled exports, internal tools). That’s where a partner like Reruption can help by building custom AI tools for marketing on top of ChatGPT, integrated with your existing stack.

For most marketing teams, the first improvements come within 2–4 weeks. In the first cycle, you use ChatGPT to clean up obvious audience overlaps, refine 3–5 core segments, and set up a structured testing plan. This alone can reduce wasted spend and stabilise ROAS.

More substantial gains typically come over 2–3 optimisation cycles (6–12 weeks), as you feed new performance data back into ChatGPT and iterate on your segment hypotheses. The more consistently you run this loop, the more your audience strategy compounds in effectiveness.

Yes, especially when you consider the alternatives. Most dedicated audience tools either require heavy integration work or lock you into proprietary black boxes. ChatGPT is relatively low-cost and flexible: you pay for usage, and you can run it directly in the browser or via API in custom workflows.

The main ROI lever is not the tool price, but the reduction in wasted media spend and the time saved on manual analysis and brainstorming. Even a modest 10–15% improvement in audience efficiency across your paid media budget will far exceed the cost of structured ChatGPT usage and lightweight enablement.

Reruption works as a Co-Preneur alongside your marketing team. We don’t just hand over a slide deck; we help you design, build, and test real AI workflows inside your organisation. For audience targeting, that can mean:

  • Running a focused AI PoC (9.900€) to prove that ChatGPT can turn your data into actionable segments and tests
  • Co-designing prompts, decision flows, and guardrails tailored to your channels, markets, and compliance needs
  • Engineering lightweight internal tools that connect ChatGPT to your CRM, analytics, or ad platforms
  • Upskilling your team so they can maintain and extend the system without constant external support

Because we operate in your P&L and work like co-founders, our focus is on measurable improvements in ROAS and acquisition cost — not theoretical AI strategies.

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