The Challenge: Manual Prospect Research

Most B2B sales teams still rely on manual prospect research. Reps jump between Google, LinkedIn, company websites, earnings calls, and PDFs to find something relevant to mention in an email or call. Each outreach can require 15–30 minutes of unfocused digging, and the results are often thin: one or two generic lines that could apply to any prospect in the same industry.

Traditional approaches no longer work because the information landscape has exploded. Prospects publish 10-Ks, ESG reports, product documentation, blog posts, interviews, and conference talks. No human can reliably scan this volume of content for every account and contact. As a result, teams either reduce research to a minimum and send generic templates, or they sacrifice outreach volume to keep personalization quality high. Neither option scales in modern, competitive markets.

The business impact is significant. Shallow personalization leads to low reply rates and weak first meetings. High-value accounts receive the same message as everyone else, so deals stall early or never open at all. Meanwhile, manual research time inflates customer acquisition costs, drags down pipeline coverage, and burns out your best reps on low-leverage work instead of high-value conversations.

The good news: this problem is real but absolutely solvable. Modern AI for sales prospecting can ingest long-form content in seconds, surface relevant pain points and initiatives, and generate natural hooks your reps can trust. At Reruption, we’ve helped organisations build AI-powered research and analysis tools in complex document environments, and the same technical patterns apply directly to manual prospect research. In the rest of this page, you’ll find practical guidance on how to use Claude to turn messy prospect data into targeted, personalized outreach at scale.

Need a sparring partner for this challenge?

Let's have a no-obligation chat and brainstorm together.

Innovators at these companies trust us:

Our Assessment

A strategic assessment of the challenge and high-level tips how to tackle it.

From Reruption’s perspective, Claude for manual prospect research is one of the most underused but highest-leverage applications of generative AI in sales. We’ve built AI-powered document research and analysis solutions in demanding environments and seen how the right setup can turn dense PDFs, reports, and transcripts into concise, actionable insights for business users. The same approach lets sales teams feed Claude long-form prospect data and receive clear briefs, buying signals, and outreach ideas in seconds instead of hours.

Think in Research Workflows, Not Just AI Emails

Many teams jump straight to “AI-generated emails” without fixing the underlying research workflow. The real leverage of Claude in sales comes from treating it as a research co-pilot that structures information before it ever writes a line of copy. That means designing a repeatable process: ingest prospect data, extract key insights, prioritize hooks, then craft tailored outreach.

Strategically, map your existing prospecting steps and identify which are high-effort but rules-based: summarizing annual reports, scanning news for triggers, comparing product portfolios, etc. These are ideal for Claude. When AI delivers a consistent research brief, you get personalization that is grounded in facts, not generic phrases, and you can swap out the email generator in the future without losing the core workflow.

Start with a Narrow, High-Value Segment

Instead of deploying Claude to every sales rep and every prospect at once, focus on one clearly defined segment: for example, your top 100 target accounts or a specific vertical where deals are large and information density is high. This keeps your AI for sales outreach experiment focused on where research quality matters most.

From a change-management perspective, a narrow segment lets you quickly compare AI-assisted prospecting against your current baseline: reply rates, meeting booked rate, and time spent per outbound touch. This controlled approach reduces risk, builds internal proof that Claude adds value, and creates internal champions who can train the broader team using real examples from your own market.

Align Sales, RevOps, and Legal Before Scaling

Using Claude for prospect research touches multiple stakeholders: Sales wants speed and personalization, RevOps manages CRM and data flows, and Legal/Compliance cares about how third-party data and internal notes are processed. Ignoring this alignment leads to shadow tools and inconsistent adoption.

Strategically, bring these teams together early. Define which data sources Claude can access (CRM fields, call notes, uploaded documents), what should remain off-limits, and how outputs should be logged back into the CRM. Document simple governance rules: what reps may copy-paste, what must be reviewed, and how to handle sensitive topics. This makes security and compliance a built-in strength instead of a blocker later.

Invest in Prompt Standards, Not Individual Hero Prompts

One of the biggest risks in AI-driven prospecting is every rep inventing their own prompts. Quality becomes inconsistent, outcomes are hard to measure, and onboarding new team members is slow. To avoid this, treat prompts as shared assets, not personal hacks.

Define a small library of standardized prompts for Claude: “create an account brief”, “analyze this call transcript”, “draft a first-touch email for X persona”, etc. These prompts should be co-designed by your top-performing reps and refined systematically based on performance. This way, your team benefits from collective intelligence, and prompt improvements compound across the entire sales organization.

Measure Impact on Pipeline Quality, Not Just Volume

When you automate manual prospect research, outreach volume will almost always increase. But the real question is: does pipeline quality improve? Strategically, your success metrics for Claude in sales prospecting should look beyond “more emails sent”.

Track leading and lagging indicators: reply rates, meetings booked, opportunities created from AI-assisted outreach, and progression rates from first meeting to later stages. Compare AI-assisted vs. non-AI cohorts. This helps you understand whether Claude is just helping reps send more messages or actually driving better conversations with better-qualified prospects.

Using Claude to automate manual prospect research is less about flashy AI emails and more about building a reliable research engine that feeds your sales team with sharp, factual insights. When you design the right workflows, prompts, and guardrails, reps can move from scattered Googling to focused, high-quality personalization that shows real understanding of each prospect.

At Reruption, we specialise in turning ideas like this into working AI solutions inside your existing sales stack — from a focused AI PoC to production-ready integrations. If you’re exploring how Claude could streamline your prospect research and outreach, we’re happy to help you validate what’s technically feasible and turn it into something your team actually uses every day.

Need help implementing these ideas?

Feel free to reach out to us with no obligation.

Real-World Case Studies

From Automotive to Fintech: Learn how companies successfully use Claude.

Cruise (GM)

Automotive

Developing a self-driving taxi service in dense urban environments posed immense challenges for Cruise. Complex scenarios like unpredictable pedestrians, erratic cyclists, construction zones, and adverse weather demanded near-perfect perception and decision-making in real-time. Safety was paramount, as any failure could result in accidents, regulatory scrutiny, or public backlash. Early testing revealed gaps in handling edge cases, such as emergency vehicles or occluded objects, requiring robust AI to exceed human driver performance. A pivotal safety incident in October 2023 amplified these issues: a Cruise vehicle struck a pedestrian pushed into its path by a hit-and-run driver, then dragged her while fleeing the scene, leading to suspension of operations nationwide. This exposed vulnerabilities in post-collision behavior, sensor fusion under chaos, and regulatory compliance. Scaling to commercial robotaxi fleets while achieving zero at-fault incidents proved elusive amid $10B+ investments from GM.

Lösung

Cruise addressed these with an integrated AI stack leveraging computer vision for perception and reinforcement learning for planning. Lidar, radar, and 30+ cameras fed into CNNs and transformers for object detection, semantic segmentation, and scene prediction, processing 360° views at high fidelity even in low light or rain. Reinforcement learning optimized trajectory planning and behavioral decisions, trained on millions of simulated miles to handle rare events. End-to-end neural networks refined motion forecasting, while simulation frameworks accelerated iteration without real-world risk. Post-incident, Cruise enhanced safety protocols, resuming supervised testing in 2024 with improved disengagement rates. GM's pivot integrated this tech into Super Cruise evolution for personal vehicles.

Ergebnisse

  • 1,000,000+ miles driven fully autonomously by 2023
  • 5 million driverless miles used for AI model training
  • $10B+ cumulative investment by GM in Cruise (2016-2024)
  • 30,000+ miles per intervention in early unsupervised tests
  • Operations suspended Oct 2023; resumed supervised May 2024
  • Zero commercial robotaxi revenue; pivoted Dec 2024
Read case study →

NYU Langone Health

Healthcare

NYU Langone Health, a leading academic medical center, faced significant hurdles in leveraging the vast amounts of unstructured clinical notes generated daily across its network. Traditional clinical predictive models relied heavily on structured data like lab results and vitals, but these required complex ETL processes that were time-consuming and limited in scope. Unstructured notes, rich with nuanced physician insights, were underutilized due to challenges in natural language processing, hindering accurate predictions of critical outcomes such as in-hospital mortality, length of stay (LOS), readmissions, and operational events like insurance denials. Clinicians needed real-time, scalable tools to identify at-risk patients early, but existing models struggled with the volume and variability of EHR data—over 4 million notes spanning a decade. This gap led to reactive care, increased costs, and suboptimal patient outcomes, prompting the need for an innovative approach to transform raw text into actionable foresight.

Lösung

To address these challenges, NYU Langone's Division of Applied AI Technologies at the Center for Healthcare Innovation and Delivery Science developed NYUTron, a proprietary large language model (LLM) specifically trained on internal clinical notes. Unlike off-the-shelf models, NYUTron was fine-tuned on unstructured EHR text from millions of encounters, enabling it to serve as an all-purpose prediction engine for diverse tasks. The solution involved pre-training a 13-billion-parameter LLM on over 10 years of de-identified notes (approximately 4.8 million inpatient notes), followed by task-specific fine-tuning. This allowed seamless integration into clinical workflows, automating risk flagging directly from physician documentation without manual data structuring. Collaborative efforts, including AI 'Prompt-a-Thons,' accelerated adoption by engaging clinicians in model refinement.

Ergebnisse

  • AUROC: 0.961 for 48-hour mortality prediction (vs. 0.938 benchmark)
  • 92% accuracy in identifying high-risk patients from notes
  • LOS prediction AUROC: 0.891 (5.6% improvement over prior models)
  • Readmission prediction: AUROC 0.812, outperforming clinicians in some tasks
  • Operational predictions (e.g., insurance denial): AUROC up to 0.85
  • 24 clinical tasks with superior performance across mortality, LOS, and comorbidities
Read case study →

Associated Press (AP)

News Media

In the mid-2010s, the Associated Press (AP) faced significant constraints in its business newsroom due to limited manual resources. With only a handful of journalists dedicated to earnings coverage, AP could produce just around 300 quarterly earnings reports per quarter, primarily focusing on major S&P 500 companies. This manual process was labor-intensive: reporters had to extract data from financial filings, analyze key metrics like revenue, profits, and growth rates, and craft concise narratives under tight deadlines. As the number of publicly traded companies grew, AP struggled to cover smaller firms, leaving vast amounts of market-relevant information unreported. This limitation not only reduced AP's comprehensive market coverage but also tied up journalists on rote tasks, preventing them from pursuing investigative stories or deeper analysis. The pressure of quarterly earnings seasons amplified these issues, with deadlines coinciding across thousands of companies, making scalable reporting impossible without innovation.

Lösung

To address this, AP partnered with Automated Insights in 2014, implementing their Wordsmith NLG platform. Wordsmith uses templated algorithms to transform structured financial data—such as earnings per share, revenue figures, and year-over-year changes—into readable, journalistic prose. Reporters input verified data from sources like Zacks Investment Research, and the AI generates draft stories in seconds, which humans then lightly edit for accuracy and style. The solution involved creating custom NLG templates tailored to AP's style, ensuring stories sounded human-written while adhering to journalistic standards. This hybrid approach—AI for volume, humans for oversight—overcame quality concerns. By 2015, AP announced it would automate the majority of U.S. corporate earnings stories, scaling coverage dramatically without proportional staff increases.

Ergebnisse

  • 14x increase in quarterly earnings stories: 300 to 4,200
  • Coverage expanded to 4,000+ U.S. public companies per quarter
  • Equivalent to freeing time of 20 full-time reporters
  • Stories published in seconds vs. hours manually
  • Zero reported errors in automated stories post-implementation
  • Sustained use expanded to sports, weather, and lottery reports
Read case study →

Citibank Hong Kong

Wealth Management

Citibank Hong Kong faced growing demand for advanced personal finance management tools accessible via mobile devices. Customers sought predictive insights into budgeting, investing, and financial tracking, but traditional apps lacked personalization and real-time interactivity. In a competitive retail banking landscape, especially in wealth management, clients expected seamless, proactive advice amid volatile markets and rising digital expectations in Asia. Key challenges included integrating vast customer data for accurate forecasts, ensuring conversational interfaces felt natural, and overcoming data privacy hurdles in Hong Kong's regulated environment. Early mobile tools showed low engagement, with users abandoning apps due to generic recommendations, highlighting the need for AI-driven personalization to retain high-net-worth individuals.

Lösung

Wealth 360 emerged as Citibank HK's AI-powered personal finance manager, embedded in the Citi Mobile app. It leverages predictive analytics to forecast spending patterns, investment returns, and portfolio risks, delivering personalized recommendations via a conversational interface like chatbots. Drawing from Citi's global AI expertise, it processes transaction data, market trends, and user behavior for tailored advice on budgeting and wealth growth. Implementation involved machine learning models for personalization and natural language processing (NLP) for intuitive chats, building on Citi's prior successes like Asia-Pacific chatbots and APIs. This solution addressed gaps by enabling proactive alerts and virtual consultations, enhancing customer experience without human intervention.

Ergebnisse

  • 30% increase in mobile app engagement metrics
  • 25% improvement in wealth management service retention
  • 40% faster response times via conversational AI
  • 85% customer satisfaction score for personalized insights
  • 18M+ API calls processed in similar Citi initiatives
  • 50% reduction in manual advisory queries
Read case study →

John Deere

Agriculture

In conventional agriculture, farmers rely on blanket spraying of herbicides across entire fields, leading to significant waste. This approach applies chemicals indiscriminately to crops and weeds alike, resulting in high costs for inputs—herbicides can account for 10-20% of variable farming expenses—and environmental harm through soil contamination, water runoff, and accelerated weed resistance . Globally, weeds cause up to 34% yield losses, but overuse of herbicides exacerbates resistance in over 500 species, threatening food security . For row crops like cotton, corn, and soybeans, distinguishing weeds from crops is particularly challenging due to visual similarities, varying field conditions (light, dust, speed), and the need for real-time decisions at 15 mph spraying speeds. Labor shortages and rising chemical prices in 2025 further pressured farmers, with U.S. herbicide costs exceeding $6B annually . Traditional methods failed to balance efficacy, cost, and sustainability.

Lösung

See & Spray revolutionizes weed control by integrating high-resolution cameras, AI-powered computer vision, and precision nozzles on sprayers. The system captures images every few inches, uses object detection models to identify weeds (over 77 species) versus crops in milliseconds, and activates sprays only on targets—reducing blanket application . John Deere acquired Blue River Technology in 2017 to accelerate development, training models on millions of annotated images for robust performance across conditions. Available in Premium (high-density) and Select (affordable retrofit) versions, it integrates with existing John Deere equipment via edge computing for real-time inference without cloud dependency . This robotic precision minimizes drift and overlap, aligning with sustainability goals.

Ergebnisse

  • 5 million acres treated in 2025
  • 31 million gallons of herbicide mix saved
  • Nearly 50% reduction in non-residual herbicide use
  • 77+ weed species detected accurately
  • Up to 90% less chemical in clean crop areas
  • ROI within 1-2 seasons for adopters
Read case study →

Best Practices

Successful implementations follow proven patterns. Have a look at our tactical advice to get started.

Standardize a Claude-Powered Account Brief Template

Start by defining what a “good” account brief looks like for your sales team. Typically this includes company overview, key initiatives, likely pain points, relevant products, decision-makers, and 2–3 outreach angles. Turn this into a structured template that Claude fills in for every new account or contact.

Have reps collect raw inputs — links to the website, LinkedIn profiles, press releases, annual reports, and any internal notes or call transcripts — and feed them into Claude in one go. Use a consistent prompt so outputs are comparable across reps and time.

Prompt template for Claude:
You are a sales research analyst helping SDRs and AEs.
Use ONLY the information provided below to create an account brief.

1. Company summary (3 sentences max)
2. Key initiatives or strategic priorities (bullets)
3. Likely pain points we can help with (bullets)
4. Recent triggers (funding, expansion, product launches, leadership changes)
5. Key stakeholders and their focus (by role if names are missing)
6. 3 specific outreach angles with short rationale

Prospect data:
[Paste website copy, LinkedIn profiles, 10-K excerpts, news, call notes, etc.]

This approach can reduce research time per account from 20–30 minutes to under 5 minutes, while increasing the depth of insights reps bring to their first touch.

Auto-Generate Persona-Specific Email and Call Hooks

Once you have a structured brief, use Claude to tailor hooks to specific personas such as CFO, CIO, Head of Operations, or VP Sales. The goal is not to automate the entire email, but to generate 2–3 sharp, personalized opening lines and call openers grounded in the brief.

Reps can then combine these hooks with your existing templates or their own style, ensuring every outreach feels personal without rebuilding from scratch each time.

Prompt template for persona hooks:
You are helping a sales rep personalize outreach.
Based on the account brief below, create:
- 3 email opening lines for a [ROLE]
- 3 short call openers for a [ROLE]
Each must reference specific details from the brief.

Account brief:
[Paste previously generated brief]

Expected outcome: faster creation of relevant, persona-specific openings that lift reply rates and call conversions compared to generic value propositions.

Summarize Long-Form Documents into Sales-Ready Insights

Claude is particularly strong at processing long documents such as 10-Ks, ESG reports, product catalogues, and webinar or call transcripts. Turn this into a repeatable workflow where a rep uploads a document, then receives a concise sales summary that connects the content to your offering.

Be explicit in your prompts that Claude should think like a salesperson: what matters is not every detail in the document, but the elements that signal priorities, constraints, and potential buying triggers.

Prompt template for document analysis:
You are an enterprise sales rep preparing for outreach.
Analyze the following document and extract ONLY sales-relevant insights.

Provide:
1. Top 5 strategic themes (short bullets)
2. 5–7 pain points or challenges we could address
3. Any metrics or quotes worth referencing in outreach
4. 3 email angles and subject lines that tie directly to the document

Document content:
[Paste 10-K, report, transcript, etc.]

This practice lets reps work effectively with information they previously ignored because it was too time-consuming to read in full.

Connect Claude Outputs Back Into Your CRM Workflow

For AI-assisted prospect research to scale, the output must live where your team actually works: the CRM. Define a simple pattern for saving Claude-generated briefs, hooks, and notes back into account and contact records. Even without full technical integration at the start, you can standardize copy-paste sections and naming conventions.

For example, every account could have a “Claude Research Brief” note with a date stamp, and every contact could have a “Claude Hooks – [Quarter/Year]” note. Over time, you can automate this flow via your CRM’s API or middleware, but even a manual process with clear standards prevents insights from being lost in chat windows or personal documents.

Suggested CRM structure:
Account Note Title: "Claude Research Brief - <YYYY-MM-DD>"
Contact Note Title: "Claude Persona Hooks - <ROLE> - <YYYY-MM-DD>"

Fields to capture:
- Top initiatives
- Pain points
- Triggers
- Outreach angles
- Best-performing subject lines (added later)

This creates a growing institutional memory of research and messaging that future reps can reuse and refine.

Implement a Quick Review Loop to Keep Outreach On-Brand

Even with strong prompts, Claude will occasionally produce phrasing or claims that don’t fully match your brand voice or positioning. Mitigate this by creating a light review loop: reps skim and adjust, and team leads periodically spot-check AI-assisted messages for quality and compliance.

Translate your brand and compliance guidelines into prompt constraints so Claude starts closer to the desired output. Over time, capture high-performing emails and use them as examples in the prompts themselves.

Prompt add-on for brand and compliance:
Follow these rules strictly:
- Tone: clear, direct, professional, no hype or exaggeration
- Do NOT promise specific ROI; use "teams often see" instead
- Avoid buzzwords; explain value in concrete terms
- Stay within 120 words unless explicitly asked otherwise

Here are 2 example emails that match our tone and style:
[Paste anonymized best-practice emails]

This keeps AI-generated personalization sharp and trustworthy, while protecting your brand and reducing the risk of overpromising.

Track AI-Assisted vs. Non-AI Outreach Performance

To understand whether Claude-powered prospect research creates real business value, tag AI-assisted outreach in your CRM or sales engagement platform. For example, add a custom field or sequence naming convention that indicates the use of AI-generated research or hooks.

On a monthly basis, compare key metrics: open and reply rates, meetings booked per 100 emails or calls, and opportunities created. Combine this with time-tracking estimates (e.g., research minutes per account) to quantify both effectiveness and efficiency gains.

Expected outcomes when well-implemented: 30–60% reduction in manual research time per prospect, 10–25% uplift in positive reply rates on targeted segments, and deeper first meetings where prospects perceive your reps as better prepared. Results will vary by market and data quality, but these ranges are realistic for teams that design their workflows and prompts carefully and integrate Claude into their day-to-day sales process.

Need implementation expertise now?

Let's talk about your ideas!

Frequently Asked Questions

Claude can ingest and analyze long-form prospect data — websites, 10-Ks, case studies, blog posts, LinkedIn profiles, and call transcripts — and turn them into concise research briefs within seconds. Instead of reps spending 20–30 minutes googling and skimming, they paste the relevant content into Claude and receive a structured summary with company context, initiatives, pain points, and suggested outreach angles.

In practice, this means your team moves from scattered, ad hoc research to a repeatable, AI-assisted workflow that consistently delivers deeper insights in a fraction of the time.

You don’t need a large data science team to start using Claude for manual prospect research. At a minimum, you need:

  • A sales lead or enablement owner who understands current prospecting workflows
  • A small group of reps willing to pilot new prompts and processes
  • Basic access to Claude and your existing tools (CRM, sales engagement, document sources)

For deeper integration (e.g. automatically loading data from your CRM or document systems), you’ll need light engineering support to connect APIs and set up secure data flows. Reruption can cover this engineering and integration work if you don’t have internal capacity.

For most teams, initial results appear within 2–4 weeks. In the first days, you create and refine core prompts for account briefs and persona-based hooks, and a small pilot group starts using Claude on real prospects. Within the first month, you can compare AI-assisted outreach against your historical benchmarks for reply and meeting rates on a defined segment.

More structural gains — such as standardized workflows, CRM integration, and consistent usage across the team — typically develop over 2–3 months. With a focused AI PoC, it’s realistic to go from idea to a working prototype that reps actually use in a matter of weeks.

ROI comes from two main levers: time saved and higher-quality conversations. Time-wise, teams often see a 30–60% reduction in manual research per prospect once workflows and prompts are in place. That either frees reps to contact more prospects or gives them more time for high-value conversations and deal strategy.

On the revenue side, better-targeted, personalized outreach can drive a 10–25% uplift in positive replies and meetings in the segments where research quality matters most (e.g. enterprise or strategic accounts). Combined, this can materially lower cost per opportunity and increase pipeline coverage without expanding headcount.

Reruption supports you end-to-end, from idea to working solution. With our AI PoC offering (9,900€), we first define and scope your specific use case for Claude in prospect research, check technical feasibility, and build a rapid prototype that your reps can test on real accounts. You receive performance metrics, an engineering summary, and a clear implementation roadmap.

Beyond the PoC, we apply our Co-Preneur approach: we embed like co-founders rather than external consultants, working directly in your sales and RevOps environment. We co-design prompts and workflows with your top reps, integrate Claude with your CRM and document systems where needed, and iterate until a solution is not just technically sound but actually used by your team in day-to-day prospecting.

Contact Us!

0/10 min.

Contact Directly

Your Contact

Philipp M. W. Hoffmann

Founder & Partner

Address

Reruption GmbH

Falkertstraße 2

70176 Stuttgart

Social Media