The Challenge: Manual Prospect Research

For most B2B sales teams, manual prospect research is a quiet productivity killer. Reps spend hours googling companies, scrolling through LinkedIn, opening annual reports, and trying to piece together who the decision makers are and what the company actually cares about right now. Every new account means another round of tab-hopping just to write a halfway relevant first email.

This worked when sales cycles were slower and territories smaller. But with modern buying committees, digital-first research, and more complex offerings, the volume and depth of information needed has exploded. Traditional approaches – spreadsheets, browser bookmarks, generic data providers and ad-hoc note taking – simply don’t keep up. They create duplicated effort across the team and still miss crucial buying signals hidden in long documents, blog posts or earnings calls.

The business impact is very real. Reps touch fewer new leads per day, and outreach often relies on shallow personalization that prospects ignore. High-potential accounts fall through the cracks because there’s no time to properly research them. Meanwhile, competitors that automate research surface better-fit accounts faster and show up with tailored messages grounded in the prospect’s current situation. The result: higher customer acquisition costs, slower pipeline generation, and a widening competitive gap.

The good news: this is exactly the kind of repetitive, information-heavy work that modern AI for sales prospecting can handle extremely well. Tools like Claude can digest dense company information, highlight buying triggers, and draft tailored talking points in minutes, not hours. At Reruption, we’ve seen how the right AI workflows can turn manual research from a bottleneck into a competitive advantage. In the rest of this guide, you’ll find practical, concrete steps to use Claude to transform prospect research and unlock more high-quality lead generation.

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Our Assessment

A strategic assessment of the challenge and high-level tips how to tackle it.

From Reruption’s experience building AI-powered research and analysis workflows, manual prospect research is a textbook case for applying Claude in sales. Claude is particularly strong at reading long, unstructured documents – company reports, blog posts, product pages, news – and turning them into clear summaries, buying signals and stakeholder maps that your sales team can actually use.

Redefine Prospect Research as a Structured, AI-Supported Process

Most sales teams treat prospect research as an individual art form: every rep has their own way of googling, reading LinkedIn and taking notes. To use Claude for lead generation effectively, you need to redefine research as a structured process with clear inputs, outputs and quality standards. Decide upfront what “good enough” research looks like for your segments: which firmographics, which key initiatives, which stakeholders, which triggers.

With that clarity, Claude becomes a force multiplier instead of a shiny toy. You can standardize prompts and research templates, ensure every rep asks the same core questions, and make outputs comparable across the team. At Reruption, this shift from ad-hoc research to defined workflows is often the single biggest unlock – AI then fills the process with speed and depth.

Start with a Narrow Pilot on One Segment or Territory

Trying to automate manual prospect research with AI across all segments at once usually leads to generic prompts and mixed results. A more strategic move is to pick one clear use case: for example, mid-market manufacturing accounts in DACH, or SaaS companies between 200–1,000 employees in the UK. Define what information matters most for that slice and design your Claude workflows around it.

A narrow pilot lets you test data sources, prompts and research depth without risking disruption to the whole team. You’ll learn how Claude handles your specific content (annual reports, industry blogs, product pages), where it excels and where human review is still required. Once you see consistent time savings and better conversations in that segment, you can generalize the patterns to other territories.

Integrate Sales, RevOps and Data Protection Early

Effective use of Claude in sales operations is not just a sales-side initiative. RevOps needs to understand how research outputs will flow into your CRM, what new fields or objects are required, and how to measure impact on lead quality and conversion. Data protection and legal teams need to validate your approach regarding public vs. internal data, retention, and compliant handling of personal information.

Bringing these stakeholders in early reduces friction later. For example, RevOps can help define a standard “AI research summary” field in your CRM, while legal can define which document types are safe to paste into Claude and where you should use self-hosted or API-based setups. At Reruption, we’ve seen pilots stall not because the technology failed, but because organizational readiness was overlooked; aligning stakeholders upfront avoids this trap.

Design for Human-in-the-Loop, Not Full Automation

Claude can dramatically accelerate prospect research automation, but fully removing humans from the loop is rarely advisable. The goal is not to auto-send AI-written emails to every scraped contact; it’s to equip reps with richer context so they can have better conversations. Strategically, you want Claude to handle the heavy lifting – document reading, summarization, trigger detection – and leave judgment, prioritization and final messaging to your salespeople.

Define specific checkpoints where humans must review or adjust AI output: for example, before updating CRM fields in bulk, before sending outreach to strategic accounts, or when the model flags ambiguous buying signals. This design reduces risk, builds rep trust in the system, and ensures that using AI for sales prospecting improves quality rather than producing high-volume but shallow outreach.

Measure Success Beyond “Time Saved”

It’s tempting to measure Claude’s impact only in hours saved on manual prospect research. While this is important, leadership should also track more strategic metrics: increase in high-fit accounts touched per week, improvement in reply rates on first-touch emails, lift in qualified opportunities generated per rep, and reduced ramp-up time for new hires.

Define these success metrics before rollout and align the team on them. This avoids the common pattern where AI tools are used sporadically and their value remains anecdotal. With clear KPIs, you can iteratively refine prompts, workflows and integrations, and confidently decide when to scale from pilot to standard operating procedure across the sales organization.

Using Claude to automate manual prospect research is less about flashy AI and more about rethinking how your sales team discovers, qualifies and approaches new accounts. When you combine clear research standards, focused pilots, human-in-the-loop review and the right KPIs, Claude can turn scattered Google searches into a repeatable system for generating better leads at scale. Reruption has helped organizations design exactly these kinds of AI-first workflows, from data sourcing to CRM integration; if you want to explore what this could look like in your environment, we’re happy to collaborate on a focused proof of concept and turn the idea into a working solution.

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Real-World Case Studies

From Aerospace to Shipping: Learn how companies successfully use Claude.

Rolls-Royce Holdings

Aerospace

Jet engines are highly complex, operating under extreme conditions with millions of components subject to wear. Airlines faced unexpected failures leading to costly groundings, with unplanned maintenance causing millions in daily losses per aircraft. Traditional scheduled maintenance was inefficient, often resulting in over-maintenance or missed issues, exacerbating downtime and fuel inefficiency. Rolls-Royce needed to predict failures proactively amid vast data from thousands of engines in flight. Challenges included integrating real-time IoT sensor data (hundreds per engine), handling terabytes of telemetry, and ensuring accuracy in predictions to avoid false alarms that could disrupt operations. The aerospace industry's stringent safety regulations added pressure to deliver reliable AI without compromising performance.

Lösung

Rolls-Royce developed the IntelligentEngine platform, combining digital twins—virtual replicas of physical engines—with machine learning models. Sensors stream live data to cloud-based systems, where ML algorithms analyze patterns to predict wear, anomalies, and optimal maintenance windows. Digital twins enable simulation of engine behavior pre- and post-flight, optimizing designs and schedules. Partnerships with Microsoft Azure IoT and Siemens enhanced data processing and VR modeling, scaling AI across Trent series engines like Trent 7000 and 1000. Ethical AI frameworks ensure data security and bias-free predictions.

Ergebnisse

  • 48% increase in time on wing before first removal
  • Doubled Trent 7000 engine time on wing
  • Reduced unplanned downtime by up to 30%
  • Improved fuel efficiency by 1-2% via optimized ops
  • Cut maintenance costs by 20-25% for operators
  • Processed terabytes of real-time data from 1000s of engines
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Upstart

Banking

Traditional credit scoring relies heavily on FICO scores, which evaluate only a narrow set of factors like payment history and debt utilization, often rejecting creditworthy borrowers with thin credit files, non-traditional employment, or education histories that signal repayment ability. This results in up to 50% of potential applicants being denied despite low default risk, limiting lenders' ability to expand portfolios safely . Fintech lenders and banks faced the dual challenge of regulatory compliance under fair lending laws while seeking growth. Legacy models struggled with inaccurate risk prediction amid economic shifts, leading to higher defaults or conservative lending that missed opportunities in underserved markets . Upstart recognized that incorporating alternative data could unlock lending to millions previously excluded.

Lösung

Upstart developed an AI-powered lending platform using machine learning models that analyze over 1,600 variables, including education, job history, and bank transaction data, far beyond FICO's 20-30 inputs. Their gradient boosting algorithms predict default probability with higher precision, enabling safer approvals . The platform integrates via API with partner banks and credit unions, providing real-time decisions and fully automated underwriting for most loans. This shift from rule-based to data-driven scoring ensures fairness through explainable AI techniques like feature importance analysis . Implementation involved training models on billions of repayment events, continuously retraining to adapt to new data patterns .

Ergebnisse

  • 44% more loans approved vs. traditional models
  • 36% lower average interest rates for borrowers
  • 80% of loans fully automated
  • 73% fewer losses at equivalent approval rates
  • Adopted by 500+ banks and credit unions by 2024
  • 157% increase in approvals at same risk level
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Cleveland Clinic

Healthcare

At Cleveland Clinic, one of the largest academic medical centers, physicians grappled with a heavy documentation burden, spending up to 2 hours per day on electronic health record (EHR) notes, which detracted from patient care time. This issue was compounded by the challenge of timely sepsis identification, a condition responsible for nearly 350,000 U.S. deaths annually, where subtle early symptoms often evade traditional monitoring, leading to delayed antibiotics and 20-30% mortality rates in severe cases. Sepsis detection relied on manual vital sign checks and clinician judgment, frequently missing signals 6-12 hours before onset. Integrating unstructured data like clinical notes was manual and inconsistent, exacerbating risks in high-volume ICUs.

Lösung

Cleveland Clinic piloted Bayesian Health’s AI platform, a predictive analytics tool that processes structured and unstructured data (vitals, labs, notes) via machine learning to forecast sepsis risk up to 12 hours early, generating real-time EHR alerts for clinicians. The system uses advanced NLP to mine clinical documentation for subtle indicators. Complementing this, the Clinic explored ambient AI solutions like speech-to-text systems (e.g., similar to Nuance DAX or Abridge), which passively listen to doctor-patient conversations, apply NLP for transcription and summarization, auto-populating EHR notes to cut documentation time by 50% or more. These were integrated into workflows to address both prediction and admin burdens.

Ergebnisse

  • 12 hours earlier sepsis prediction
  • 32% increase in early detection rate
  • 87% sensitivity and specificity in AI models
  • 50% reduction in physician documentation time
  • 17% fewer false positives vs. physician alone
  • Expanded to full rollout post-pilot (Sep 2025)
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Goldman Sachs

Investment Banking

In the fast-paced investment banking sector, Goldman Sachs employees grapple with overwhelming volumes of repetitive tasks. Daily routines like processing hundreds of emails, writing and debugging complex financial code, and poring over lengthy documents for insights consume up to 40% of work time, diverting focus from high-value activities like client advisory and deal-making. Regulatory constraints exacerbate these issues, as sensitive financial data demands ironclad security, limiting off-the-shelf AI use. Traditional tools fail to scale with the need for rapid, accurate analysis amid market volatility, risking delays in response times and competitive edge.

Lösung

Goldman Sachs countered with a proprietary generative AI assistant, fine-tuned on internal datasets in a secure, private environment. This tool summarizes emails by extracting action items and priorities, generates production-ready code for models like risk assessments, and analyzes documents to highlight key trends and anomalies. Built from early 2023 proofs-of-concept, it leverages custom LLMs to ensure compliance and accuracy, enabling natural language interactions without external data risks. The firm prioritized employee augmentation over replacement, training staff for optimal use.

Ergebnisse

  • Rollout Scale: 10,000 employees in 2024
  • Timeline: PoCs 2023; initial rollout 2024; firmwide 2025
  • Productivity Boost: Routine tasks streamlined, est. 25-40% time savings on emails/coding/docs
  • Adoption: Rapid uptake across tech and front-office teams
  • Strategic Impact: Core to 10-year AI playbook for structural gains
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UC San Francisco Health

Healthcare

At UC San Francisco Health (UCSF Health), one of the nation's leading academic medical centers, clinicians grappled with immense documentation burdens. Physicians spent nearly two hours on electronic health record (EHR) tasks for every hour of direct patient care, contributing to burnout and reduced patient interaction . This was exacerbated in high-acuity settings like the ICU, where sifting through vast, complex data streams for real-time insights was manual and error-prone, delaying critical interventions for patient deterioration . The lack of integrated tools meant predictive analytics were underutilized, with traditional rule-based systems failing to capture nuanced patterns in multimodal data (vitals, labs, notes). This led to missed early warnings for sepsis or deterioration, higher lengths of stay, and suboptimal outcomes in a system handling millions of encounters annually . UCSF sought to reclaim clinician time while enhancing decision-making precision.

Lösung

UCSF Health built a secure, internal AI platform leveraging generative AI (LLMs) for "digital scribes" that auto-draft notes, messages, and summaries, integrated directly into their Epic EHR using GPT-4 via Microsoft Azure . For predictive needs, they deployed ML models for real-time ICU deterioration alerts, processing EHR data to forecast risks like sepsis . Partnering with H2O.ai for Document AI, they automated unstructured data extraction from PDFs and scans, feeding into both scribe and predictive pipelines . A clinician-centric approach ensured HIPAA compliance, with models trained on de-identified data and human-in-the-loop validation to overcome regulatory hurdles . This holistic solution addressed both administrative drag and clinical foresight gaps.

Ergebnisse

  • 50% reduction in after-hours documentation time
  • 76% faster note drafting with digital scribes
  • 30% improvement in ICU deterioration prediction accuracy
  • 25% decrease in unexpected ICU transfers
  • 2x increase in clinician-patient face time
  • 80% automation of referral document processing
Read case study →

Best Practices

Successful implementations follow proven patterns. Have a look at our tactical advice to get started.

Standardize an AI-Ready Prospect Research Template

Before you open Claude, define a standard template for what a good prospect profile looks like. For example: company overview, key initiatives, product lines, ICP fit analysis, key stakeholders, recent triggers (funding, expansions, leadership changes), and suggested angles for outreach. Document this in a simple text or markdown format – Claude works very well with clear structures.

Then, instruct reps to always ask Claude to fill this template rather than improvising new questions for every account. This reduces variance and speeds up adoption. A simple starting prompt could be:

You are a sales research assistant helping SDRs and AEs prepare for outreach.

Goal: Fill in the following prospect research template based on the information I provide.

Template:
1. Company snapshot (2-3 sentences)
2. Core products/services
3. Target customers & markets
4. Recent news & strategic initiatives (max 5 bullet points)
5. Signs of fit with our ICP (list criteria explicitly)
6. Likely buying committee & key decision makers (roles, not names unless obvious)
7. 3-5 specific talking points for first outreach
8. Potential risks or disqualifiers

Use concise bullet points. If information is missing, state "Not enough data" rather than guessing.

Expected outcome: every rep gets a structured, comparable summary for each account within minutes, and leadership can inspect quality across the team.

Feed Claude High-Quality Source Material, Not Just URLs

Claude performs best when you provide it with the actual text you want it to analyze. Instead of just pasting a homepage URL, copy relevant sections from the website, blog posts, product pages, job listings, and – where available – parts of annual or sustainability reports. For larger teams, RevOps can prepare a short internal checklist of "mandatory sources" per account type.

Use prompts that explicitly reference the pasted content and instruct Claude not to hallucinate beyond it:

You will receive several chunks of text about a prospect (website copy, blog posts, job listings, reports).

Task:
1. Read ALL content.
2. Extract only facts that are explicitly stated.
3. Based on these facts, fill the research template.
4. Mark any assumptions clearly as "Assumption".

Here is the content:
---
[PASTE TEXT SNIPPETS HERE]
---

This approach minimizes guesswork and keeps your AI-driven prospect research grounded in verifiable information.

Use Claude to Score Fit and Prioritize Accounts from CSV Exports

Many teams export leads from LinkedIn, events or intent tools into CSVs and then manually scan them for relevance. Claude can analyze these CSV snippets and assign an ICP fit score, helping reps prioritize their day. Start by defining your ICP criteria (industry, size, tech stack, geography, existing tools) and encode them directly in the prompt.

An example workflow: export 50–200 leads, copy a subset of rows into Claude, and ask for a scored and sorted list:

You are assisting a sales team with lead scoring.

I will paste a CSV excerpt with the following columns:
Company, Website, Industry, Employee_Count, Country, Job_Title, Seniority

Our ICP (Ideal Customer Profile):
- Industries: Manufacturing, Logistics, B2B Tech
- Employee_Count: 200-5000
- Countries: DACH & Benelux
- Seniority: Director level and above

Tasks:
1. For each row, assign a Fit_Score from 1-10 based on the ICP.
2. Briefly justify the score in 1 sentence.
3. Return the data as a markdown table sorted by Fit_Score descending.

Here is the CSV excerpt:
[PASTE CSV ROWS]

Expected outcome: reps focus first on 8–10 fit accounts instead of scanning all 200 manually, significantly increasing effective activity on high-potential leads.

Generate Hyper-Relevant Talking Points and Email Openers

Once Claude has processed company information, you can ask it to generate concrete talking points and personalized openers anchored in the prospect’s context. The key is to connect research output with your value proposition and avoid generic flattery or buzzwords.

Use prompts that reference both the research summary and your offering:

You are helping a sales rep craft relevant outreach.

Context about our product/service:
[ADD 3-5 BULLETS ON YOUR OFFERING]

Here is the research summary for the prospect:
[PASTE CLAUDE'S RESEARCH OUTPUT]

Tasks:
1. Create 5 concise talking points that link the prospect's situation to our value.
2. Draft 3 alternative opening sentences for a cold email.
   - Each opener must reference a specific fact from the research.
   - Avoid generic phrases like "I hope this email finds you well".
3. Keep language natural and non-pushy.

This turns raw insight into practical, on-message content your reps can directly use in emails, calls and LinkedIn outreach.

Embed Claude Outputs into Your CRM Workflow

To move beyond copy-paste experimentation, connect Claude’s outputs with your CRM. Even without a full API integration, you can standardize where research lives: for example, a dedicated "AI Research" field on the account record, and a "Talking Points" field on contacts. Reps paste Claude’s structured output into these fields so the whole team benefits from the research.

As you mature, you can work with engineering or partners like Reruption to trigger Claude via API when a new account is created or when specific fields are updated. The API receives company data, runs your standardized prompt, and writes the structured summary back to CRM automatically. This keeps AI prospect research aligned with your existing sales process instead of living in separate documents or chat windows.

Set Guardrails and Review Routines for Quality and Compliance

Finally, define explicit guardrails for how Claude should be used in prospect research. For example: only public information may be pasted, no sensitive internal documents without a vetted setup, and clear labeling of AI-generated notes in the CRM. Train reps to quickly review outputs for accuracy and tone before using them in customer-facing communication.

A simple weekly routine can sustain quality: team leads pick a few accounts, compare Claude’s summaries and talking points with actual calls and outcomes, and adjust prompts based on what worked. Over time, this feedback loop sharpens your prompts, reduces noise, and ensures AI for sales prospecting remains a trusted asset rather than an unchecked automation.

Expected outcomes when these best practices are implemented together: 30–50% reduction in time spent on manual prospect research per rep, 20–30% more high-fit accounts touched per week, and measurable lift in reply and meeting-booked rates from more relevant outreach – without adding headcount.

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Frequently Asked Questions

Claude can take over the most time-consuming parts of manual prospect research: reading long web pages, reports, blog posts and job listings, extracting key facts, and organizing them into a consistent template. Instead of each rep googling and taking unstructured notes, they paste relevant content into Claude and receive a clear summary, ICP fit assessment and suggested talking points within minutes.

In practice, teams typically see research time per account drop from 20–30 minutes to 5–10 minutes, while improving the depth and structure of the insights captured. The rep still decides how to use this information – but they start from a much stronger, faster foundation.

You don’t need a data science team to start using Claude for sales prospecting, but you do need three things: clear ICP and research criteria, someone to design and test good prompts, and basic enablement for your reps. At minimum, a sales or RevOps lead can work with 1–2 motivated reps to define a research template and initial prompts.

Over time, you can involve IT or engineering to connect Claude more deeply to your CRM or data sources via API, but this is not mandatory for a successful first phase. Reruption often helps clients with this setup: from defining the right templates to creating a first set of reusable prompts and workflows that fit your existing tools.

For most organizations, the first impact is visible within a few weeks. In week one, you define your research template, prompts and basic guardrails. In weeks two and three, a pilot group of reps uses Claude daily on a specific segment and you compare their activity and outcomes to a control group.

Realistic early results include: more accounts researched per day, richer notes in the CRM, higher quality of first-touch messages, and faster ramp-up for new reps. Pipeline and revenue effects typically lag by one to three quarters, depending on your sales cycle length, but you’ll see leading indicators like increased reply and meeting-booked rates much earlier.

The direct cost of using Claude (license or API usage) is usually small compared to sales headcount. The main investment is in designing the right workflows, prompts and integrations so that AI prospect research actually fits your process. Many teams start with a lightweight setup and only invest in deeper integration once they see clear benefits.

In terms of ROI, a realistic target is a 30–50% reduction in time spent on research and a 10–20% increase in qualified opportunities per rep over time, driven by higher activity on better-fit accounts and more relevant outreach. For most B2B sales motions, converting even a handful of additional high-quality deals per year easily covers the initial investment in tooling and enablement.

Reruption supports companies end-to-end in turning Claude into a practical sales research assistant. With our AI PoC offering (9,900€), we start by defining a concrete use case – for example, automating prospect research for one segment – and then build a working prototype within days. This includes model and architecture choices, prompt design, performance evaluation and a realistic production plan.

Beyond the PoC, our Co-Preneur approach means we embed with your team like co-founders: we sit with your reps, refine research templates and prompts based on real calls, connect Claude to your existing tools, and ensure security and compliance requirements are met. The outcome is not a slide deck, but a functioning AI workflow that your sales organization can rely on to replace manual prospect research with a faster, smarter system.

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